Publications and Grants

Publications

Wang J. Exploring Cohesin-Related Multiomics Information in the Web Browser. Methods in Molecular Biology, 2024, doi:10.1007/978-1-0716-4136-1_25
Wang J, Chen H. Extracting Chromosome Structural Information as One-Dimensional Metrics and Integrating Them with Epigenomics. Methods in Molecular Biology, 2024, doi:10.1007/978-1-0716-4136-1_25
Wang J, Nakato R. Churros: A docker-based large-scale epigenome analysis pipeline DNA Research, 2024, 31, 1-11.
Nakato R#, Sakata T#, Wang J, et.al. Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors Nature Communications, 2023, 14 (1), 5647
Wang J, Nakato R. Comprehensive multiomics analyses reveal pervasive involvement of aberrant cohesin binding in transcriptional and chromosomal disorder of cancer cells. iScience, vol 26, issue 6, 2023.
Wang J, Nakato R. CohesinDB: a comprehensive database for decoding cohesin-related epigenomes, 3D genomes and transcriptomes in human cells. Nucleic Acids Research, gkac795, 2022
Nakato R#, Sakata T#, Wang J, et.al. Context-dependent 3D genome regulation by cohesin and related factors. bioRxiv, preprint, 2022.
Wang J, Bando M, Shirahige K, Nakato R. Large-scale multi-omics analysis suggests specific roles for intragenic cohesin in transcriptional regulation. Nature Communications, 2022, 13(1): 1-13., 2022.
Wang J, Nakato R. HiC1Dmetrics: framework to extract various one-dimensional features from chromosome structure data. Briefings in Bioinformatics, bbab509, 2021.
Wang J#, Wen S#, et.al. Novel combination of histone methylation modulators with synergistic therapeutic activity against acute myeloid leukemia in vitro and in vivo. Cancer Letters, 2017, 413:35-45. # Co-first author. (Wen S is my supervisor of Master course, I did all experiment, analysis and wrote the paper.)
Wang J, Luo B, Li X, et.al., Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells. Cell Death & Disease, 2017 Jun 22;8(6):e2887.
Luo B#, Wang J#, et.al. New Mild and Simple Approach to Isothiocyanates: A Class of Potent Anticancer Agents. Molecules, 2017 Jun 1;22(6). pii: E773. # Co-first author

Grants

国家自然科学基金，青年项目，2025-2028，主持，在研
广东省区域联合基金，青年项目，2024-2026，主持，在研
广东省区域联合基金，面上项目，2025-2028，主持，在研
湖南省自然科学基金，青年项目，2024-2026，主持，在研
长沙市自然科学基金，第一批， 2024-2026，主持，在研
湖南大学，高层次人才启动基金，2023–2031，主持，在研

Conference presentation

Wang J, et al, TICHR: Transcriptional regulation analysis by the integration of ChIP-seq, Hi-C and RNA-seq. the 4th Hi-C Workshop, Chiba, Japan, November, 2024
Wang J, et al, Churros: A docker-based large-scale epigenome analysis pipeline. MBSJ2023, Kobe, Japan, December, 2023
Wang J, et al, Investigating Hi-C contacts within and between TADs by quantitative methods. Genome building from TADs, Tsukuba, Japan, January, 2023
Wang J, et al, Computational solutions for integrated analysis of multi-omics next-generation sequencing data. MBSJ 2022, Chiba, Japan, December, 2022
Wang J, et al, Multi-omics data-driven analysis reveals specific roles of cohesin in human diseases. IIBMP 2022, Osaka, Japan, September, 2022
Wang J, et al, Pervasive role of cohesin binding in the dysregulation of cancer gene expression. 東京大学生命科学シンポジウム, Tokyo, Japan, June, 2022
Wang J, et al, Aberrant cohesin binding is pervasively implicated in the dysregulation of chromosome structure and gene expression in cancer. The 74th Annual meeting of Japan Society for Cell Biology, Funabori, Japan, June, 2022
Wang J, et al, A comprehensive multi-omics analysis reveals a pervasive role of cohesin binding sites in the dysregulation of cancer gene expression. The 15th Annual Meeting of Japanese society for Epigenetics, Kyushu, Japan, June, 2022
Wang J, et al, HiC1Dmetrics: framework to extract various one-dimensional features from chromosome structure data. 39th Chromosome Workshop, Online, Japan, Dec, 2021
Wang J, et al, Pan-cancer analysis suggest conserved and changed cohesin bindings with oncogenic functions. MBSJ2021, Yokohama, Japan, Dec, 2021
Wang J, et al, HiC1Dmetrics: Using 1D metrics to describe different structure from Hi-C data. Riken BDR, Online, Japan, Mar, 2021
Wang J, et al, HiC1Dmetrics: identifying directional topologically associating domains with unique transcriptional activity, MBSJ2020, Nagoya (online), Japan, Dec 2020
Wang J, et al, A novel function of cohesin on intragenic regions for tissue-specific gene transcription,細胞ダイバース第3回若手ワークショップ, Atami, Japan, Feb, 2020
Wang J, et al (Winner of Keystone Scholarship), Large-scale epigenomics analysis suggests an important role of intragenic cohesin in tissue-specific transcription. Keystone Symposia “Chromatin Architecture and Chromosome Organization (X5), Whistler, BC Canada, Mar, 2020.
Wang J, et al, Integrated analysis of large-scale epigenomics to classify cohesin functions in breast cancer cells,The 42nd Annual Meeting of the Molecular Biology Society of Japan, Fukuoka, Japan, Dec, 2019.